BIOENGINEER

New Algorithm Zooms Across Scales to Reveal Hidden Signals in Spatial Genomics

Researchers have developed SpatialZoomer, a spectral graph-based tool that automatically identifies the biologically ...
Science

Preclinical and first-in-human evaluation of VG-3927/SAR448851, an oral small-molecule TREM2 agonist for Alzheimer’s disease

Microglial dysfunction is increasingly implicated in Alzheimer’s disease (AD) pathogenesis, with loss-of-function variants in ...
Science

Metabolomic aging and mortality clocks based on ensemble learning identify systemic aging risk across the human life span in 18,476 individuals

Plasma metabolomic profiling across the human life span yields two aging metrics linked to chronic disease and mortality.